Israeli airstrikes struck the central Gaza Strip and the city of Rafah overnight into Friday, resulting at least 22 fatalities, witnesses and hospital officials said.

The overnight airstrikes came hours after U.S. President Joe Biden said Thursday that he considers Israel’s conduct in the war to be “over the top.”

“I am of the view, as you know, that the conduct of the response in the Gaza Strip has been over the top,” Biden told reporters in exchange on Thursday evening after delivering remarks on a special counsel report on his handling of classified documents.

U.S. Secretary of State Antony Blinken left Israel on Thursday as the divide grows between the two close allies on the way forward.

More than half of Gaza’s population of 2.3 million has been driven by Israel’s military offensive toward the border with Egypt. Unable to leave the tiny Palestinian territory, many are living in makeshift tent camps or overflowing U.N.-run shelters.

The Palestinian death toll from the war has surpassed 27,840 people, the Health Ministry in Gaza said. A quarter of Gaza’s residents are starving.

The U.N. children’s agency called on all parties to refrain from military escalation in Rafah, at the southern edge of the Gaza Strip, warning that there are more than 600,000 children in the area, some of whom have been displaced more than once since the war began four months ago.

The war began with Hamas’ assault into Israel on Oct. 7, in which militants killed about 1,200 people, mostly civilians, and abducted around 250. Hamas is still holding more than 130 hostages, but around 30 of them are believed to be dead.

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